Open Rank- Research Instructor, Sr. Research Instructor

University of Colorado Anschutz Medical Campus

Department: Biomedical Informatics

Job Title: Open Rank- Research Instructor, Sr. Research Instructor

Position #00826395: - Requisition #:34874

Job Summary:

The University of Colorado Cancer Center is seeking a bioinformatics researcher with experience in one or more of these areas: bioinformatics analysis, algorithm development, and/or pipeline development and application. The ideal candidate will have applied or developed bioinformatics methods applicable to cancer research in at least one, but preferably several -omics types. We have particular interest in individuals with expertise in bulk and/or single cell transcriptomics. This position will be part of a team of highly experienced bioinformatics analysts that work across an array of -omics technologies. The ideal candidate will be able to effectively collaborate, organize, and lead the analysis across multiple projects. This position will also offer the opportunity for learning and growth in cutting edge technologies and cancer biology through active collaborations.

This position will be fully supported by the Cancer Center. The Bioinformatics team works in a hybrid environment and this position will allow for a combination of in person and remote work with at least 1 day per week in the office.

Examples of Duties Performed

Bioinformatics and Data Analysis (80%)

• Provide the bioinformatics expertise and leadership in study design, study oversight, data management, data analysis and manuscript preparation to assist all levels of biomedical investigators and clinicians on new research activities across a wide range of disciplines
• Collaborate with and support Principal Investigators (PI) and other stakeholders in the area of bioinformatics and data analysis
• Perform scientifically rigorous data management and bioinformatic analyses
• Develop and disseminate a variety of tools designed to access relevant clinical and sample data
• Develop and implement complex analysis pipelines, programming, and data visualization techniques for multi-layered -omics datasets (transcriptome, epigenome, proteome, microbiome, etc.)
• Assist with the design and development of bioinformatics-related programming projects and analysis pipelines
• Write custom scripts to access databases and analyze data
• Independently and creatively identify bioinformatic and data management solutions
• Provide method, figure, and analysis write ups for papers and grants
• Actively track the projects, report findings, and communicate progress with collaborating investigators

Process Improvement and Leadership (20%)

• Assist Team Leads, Supervisors and/or management with creation and implementation of processes and procedures and quality improvement initiatives
• Assist and train junior team members
• Assist with developing or develop protocol-specific systems and documents including process flows, training manuals, and Standard Operating Procedures (SOPs). Maintain subject level documentation and prepares documents, equipment and/or supplies
• Assist with identifying issues related to operational efficiency and share results with leadership
• Prepare for, attend, and contribute to weekly group meetings

Work Location:

Hybrid - this role is eligible for a hybrid schedule of #1 days per week on campus and as needed for in-person meetings.

Why Join Us:

The University of Colorado (CU) Cancer Center is part of the CU School of Medicine headquartered at the Anschutz Medical Campus. It is Colorado's only National Cancer Institute-designated comprehensive cancer center , a distinction recognizing its outstanding contributions to research, clinical trials, prevention and cancer control. CU Cancer Center's clinical care sites are UCHealth, University of Colorado Hospital and Children's Hospital Colorado, all which are ranked nationally by U.S. News and World Report .

The CU Cancer Center (UCCC) has a membership of over 280 faculty that span research from basic cancer biology to epidemiology and cancer prevention. The University has made major investments into centralizing patient medical records for research purposes, bringing in cutting edge single cell technologies at the protein, DNA, and RNA level (10x Genomics, next-gen sequencing, nanopore sequencing, VECTRA, MIBI, mass spectrometry, mass cytometry, high content microscopy), made major investments in to building research programs in Immuno-oncology, data analytics, RNA biosciences, and Fibrosis. The UCCC is committed to developing cutting edge basic research and translating these findings into the clinic.

UCCC is a member of the prestigious National Comprehensive Cancer Network , an alliance of the nation's leading cancer centers working to establish and deliver the gold standard in cancer clinical guidelines. CU Cancer Center also is a member of the Oncology Research Information Exchange Network (ORIEN), a unique research partnership among North America's top cancer centers leveraging multiple data sources and matching patients to targeted treatments. CU Cancer Center includes six institutional partners made up of approximately 300 researchers and physicians at three state universities and three healthcare delivery institutions.

The CU Cancer Center's vision is to "Prevent and conquer cancer. Together." We do this through our mission statement of "uniting our community to overcome cancer through innovation, discovery, prevention, early detection, multidisciplinary care and education."

Why work for the University?

We have AMAZING benefits and offerexceptional amounts of holiday, vacation and sick leave! The University of Colorado offers an excellent benefits package including:

• Medical: Multiple plan options
• Dental: Multiple plan options
• Additional Insurance: Disability, Life, Vision
• Retirement 401(a) Plan: Employer contributes 10% of your gross pay
• Paid Time Off: Accruals over the year
• Vacation Days: 22/year (maximum accrual 352 hours)
• Sick Days: 15/year (unlimited maximum accrual)
• Holiday Days: 10/year
• Tuition Benefit: Employees have access to this benefit on all CU campuses
• ECO Pass: Reduced rate RTD Bus and light rail service

There are many additional perks & programs with the CU Advantage .

Diversity and Equity:

The University of Colorado Anschutz Medical Campus is committed to recruiting and supporting a diverse student body, faculty and administrative staff. The university strives to promote a culture of inclusiveness, respect, communication and understanding. We encourage applications from women, ethnic minorities, persons with disabilities, persons within the LGBTQ+ community and all veterans. In addition, the Anschutz Campus has also been recognized as an Age-Friendly University. The University of Colorado is committed to diversity and equality in education and employment.

Qualifications:

Minimum Qualifications

Applicants must meet minimum qualifications at the time of hire.

This is an open rank position and could be categorized as Research Instructor, Senior Research Instructor based on experience and qualifications as indicated below:

Research Instructor

• PhD or equivalent experience in Bioinformatics, Computational Biology, Pharmacology, Cancer Biology or related fields
• Three (3) years bioinformatics analyses experience

Senior Research Instructor

• PhD or equivalent experience in Bioinformatics, Computational Biology, Pharmacology, Cancer Biology or related fields
• Five (5) years bioinformatics analyses experience

Preferred Qualifications

• PhD in Bioinformatics, Biostatistics, Computational Biology or related fields
• Experience analyzing data using a programming language, such as R or python
• Experience with the analysis of multiple -omics types, with high preference to single cell and bulk transcriptomics
• Experience with Seurat and other single cell analysis R packages
• Experience with high-performance computing
• A publication record in cancer research
• Demonstrated ability to train researchers in bioinformatics skills and techniques
• An active GitHub repository and experience with working in a software development team
• A published example of a developed algorithm, pipeline, or database with application to -omics or image data

Competencies, Knowledge, Skills, and Abilities

• Expert knowledge of basic statistical principles relevant in biomedical research
• Expert ability to analyze and solve complex problems and apply quantitative analytical approaches
• Demonstrated fluency in one or more programming languages (e.g., R, Python, Perl, Java, C++) and willingness to learn new programming languages as necessary
• Familiarity with statistical analytical concepts and methods
• Ability to communicate effectively, both in writing and orally
• Ability to establish and maintain effective working relationships with employees at all levels throughout the institution
• Ability to manage multiple simultaneous projects and communicate progress on all projects in a consistent timeframe.
• Outstanding people skills
• Ability to interpret and master complex research protocol information
• Expert understanding in a highly relevant field in cancer research, such as immunology, developmental biology, cell signaling, or a specific cancer type (e.g., prostate, breast)
• Interest in developing new analytical workflows for emerging technologies (e.g., multiplexed ion beam imaging or single cell technologies)

How to Apply:

For full consideration, please submit the following document(s):

• A letter of application which specifically addresses the job requirements and outlines qualifications
• A current CV/resume
• List of three to five professional references (we will notify you prior to contacting both on and off-list references)
• If available, provide a link to an open source code repository, for example, on GitHub, to demonstrate previous contributions.

Applications are accepted electronically ONLY at .

Questions should be directed to: James Costello,

Screening of Applications Begins:

Immediately and continues until position is filled. For best consideration, apply by March 12, 2025.

Anticipated Pay Range:

The starting salary range ( or hiring range ) for this position has been established as HIRING RANGE:

Research Instructor: $100,000-120,000

Sr. Research Instructor: $100,000-200,000

The above salary range ( or hiring range ) represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting. This position is not eligible for overtime compensation unless it is non-exempt.

Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.

Total Compensation Calculator:

ADA Statement:

The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act, please contact the Human Resources ADA Coordinator at .

Background Check Statement:

The University of Colorado Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees.

Vaccination Statement:

CU Anschutz strongly encourages vaccination against the COVID-19 virus and other vaccine preventable diseases . If you work, visit, or volunteer in healthcare facilities or clinics operated by our affiliated hospital or clinical partners or by CU Anschutz, you will be required to comply with the vaccination and medical surveillance policies of the facilities or clinics where you work, visit, or volunteer, respectively. In addition, if you work in certain research areas or perform certain safety sensitive job duties, you must enroll in the occupational health medical surveillance program .